A collaborative project driven by researchers of the Max Perutz Labs Vienna, a joint venture of the University of Vienna and the Medical University of Vienna, and the TU Wien (Vienna) resulted in a new tissue clearing technique that lets researchers look deep into animal organs and nervous systems.
The researchers have found a way to remove a range of common pigment types in tissue, enabling them to get high-resolution 3D-images of cells and tissue without the need for sectioning.
To look deep into the animals, they use a customized light-sheet microscope based on a SuperK laser and SuperK VARIA tunable filter.
Read how and see the 3D-videos in the case story.