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Take a deep look into animal organs and nervous systems

New research in neuroscience and microscopy allows researchers to look deep into animal organs and nervous systems – from squids and worms to fish and salamanders.

Zebrafish

A collaborative project driven by researchers of the Max Perutz Labs Vienna, a joint venture of the University of Vienna and the Medical University of Vienna, and the TU Wien (Vienna) resulted in a new tissue clearing technique that lets researchers look deep into animal organs and nervous systems.

The researchers have found a way to remove a range of common pigment types in tissue, enabling them to get high-resolution 3D-images of cells and tissue without the need for sectioning.

To look deep into the animals, they use a customized light-sheet microscope based on a SuperK laser and SuperK VARIA tunable filter.

Read how and see the 3D-videos in the case story.