Supercontinuum OCT used to measure retinal oxygen metabolic response in the eye

Using the SuperK EXTREME OCT supercontinuum laser from NKT Photonics, a research team from Northwestern University and University of Wisconsin has build a visible light optical coherence tomography imaging system capable of measuring retinal oxygen metabolic rate (rMRO2) noninvasively in rat eyes. Being able to quantify oxygen metabolism noninvasively is important for diagnostics and investigation of a range of eye diseases such as age-related macular degeneration, diabetic retinopathy and glaucoma.

The ability to quantitatively measure oxygen metabolism will further expand the applications of supercontinuum powered OCT. Vis-OCT provides a convenient approach that allows both blood flow and sO2 quantification with one noninvasive setup, which would otherwise either be invasive or requires different imaging systems.

Read more in their Nature paper: Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation