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Super-resolution microscopy with a SuperK laser

Interleaved laser pulses give super-resolution microscopy for single-molecule spectroscopy and localization.

Microscope

Until now, MINFLUX is the most precise and most photon-efficient way to localize fluorescent molecules. But there’s a new kid on the block.

In a transatlantic collaboration, Professor Tinnefeld’s groups of the LMU Munich and Professor Stefani’s group of the University of Buenos Aires, have worked together to further improve MINFLUX nanoscopy.

They invented p-MINFLUX – the pulsed interleaved MINFLUX.

Read how doughnut-shaped excitation profiles and a SuperK supercontinuum laser made it possible.