Techniques typically used for cellular research Confocal microscopy FLIM/FRET Single Molecule Spectroscopy OCT (histology) STED microscopy HCS Flow Cytometry CARS Multi-photon excitation Contact us now Supercontinuum lasers for cellular research Filters and accessories for supercontinuum lasers
White light sources have allowed users to illuminate, interrogate, and excite biological materials and chemicals for several hundred years. Traditionally, filament or gas discharge lamps have been used and they are today supplemented by LEDs and other white light sources. However, the output power and/or bandwidth of these sources remain inadequate for many applications.
Lasers provide excellent beam quality and power but they are inherently single wavelength devices. To address several wavelengths one must combine a number of lasers adding cost and complexity. Moreover, only certain discrete wavelengths are available.
The supercontinuum white light laser combines the broadband nature of the lamp with the power and robustness of a laser and has been used in bio-photonics since their introduction to the market by NKT Photonics in 2003. A supercontinuum laser typically provides a continuous output in the entire 400-2400nm range and by filtering one can address any part of the spectrum individually. The diffraction limited output is fiber delivered with a typical spectral density of several mW/nm – many orders of magnitude brighter than lamp-based sources and the total power can reach several Watt. Moreover, since supercontinuum lasers are monolithic fiber lasers, they require no alignment or service and NKTs sources have lifetimes exceeding thousands of hours.
Preclinical imaging is the visualization of living animals for research purposes, such as drug development. Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, in animals responding to physiological or environmental changes. Publications Non-invasive imaging and monitoring of rodent retina using simultaneous dual-band... Read more »
Ophthalmology is the branch of medicine that deals with the anatomy, physiology and diseases of the eye. Techniques used in ophthalmology Optical Coherence Tomography (OCT) Learn more about the basic principles of supercontinuum powered OCT. Publications Summary Ji Yi, 2013; Visible-light optical coherence tomography for retinal oximetry Using SuperK as OCT light to extract hemoglobin oxygen... Read more »